详细介绍


陈豪华,男,博士,讲师

邮箱:chenhaohua@htu.edu.cn

地址:kaiyun欧洲杯app实训楼606




教育经历:

2013.9-2017.6  海南师范大学  理学学士

2017.9-2023.6  重庆大学    硕博连读   导师:蓝宇教授


工作经历:

2023.7-至今 kaiyun欧洲杯app


研究领域与兴趣:

1.过渡金属催化偶联反应和环加成反应的机理及选择性研究;

2.有机小分子催化的不对称反应:理论导向的催化体系优化与设计;

3.有机转化的分子动力学模拟。


代表性论文:

(1). Zhou, W.#; Xi, S.#; Chen, H.#; Jiang, D.; Yang, J.; Liu, S.; He, L.; Qiu, H.; Lan, Y.; Zhang, M. A Bridged Backbone Strategy Enables Collective Syntheses of Strychnan Alkaloids. Nat. Chem. 2023, 15, 1074–1082 (共同一作.)

(2). Xiong, Y.#; Du, Z.#; Chen, H.#; Yang, Z.; Tan, Q.; Zhang, C.; Zhu, L.; Lan, Y.; Zhang, M. Well-Designed Phosphine–Urea Ligand for Highly Diastereo- and Enantioselective 1,3-Dipolar Cycloaddition of Methacrylonitrile: A Combined Experimental and Theoretical Study. J. Am. Chem. Soc.2019, 141, 961-971.(共同一作)

(3). Xi, S.#; Dong, J.#; Chen, H.#; Dong, Q.; Yang, J.; Tan, Q.; Zhang, C.; Lan, Y.; Zhang, M. Lewis acid–catalyzed domino generation/[2,3]-sigmatropic rearrangement of ammonium ylidesto access chiral azabicycles. Sci. Adv.2021, 7, eabd5290. (共同一作)

(4). Chen, H.; Li, Y.; Liu, S.; Xiong, Q.; Bai, R.; Wei, D.; Lan, Y. On the mechanism of homogeneous Pt-catalysis: A theoretical view. Coor. Chem. Rev. 2021, 437, 213863.

(5). Chen, H.; Zhang, T.; Shan, C.; Liu, S.; Song, Q.; Bai, R.; Lan, Y. Mechanism of Brønsted-Base-Mediated Borylation of Propynols: A DFT Study. Org. Lett.2019, 21, 4924-4928.

(6). Chen, H.#; Zhu, L.#; Zhong, K.; Yue, X.; Qu, L.-B.; Bai, R.; Lan, Y. Theoretical insight into phosphoric acid-catalyzed asymmetric conjugate addition of indolizines to α,β-unsaturated ketones. Chin. Chem. Lett.2018, 29, 1237-1241.

(7). Li, J. #;Chen, H.#; Zhong, Rong.; Zhu, L.; Liu, S; Ding, H.; Yang, J.; Wang, L.; Lan, Y.; Wang, Z. Perfluoroarene Interaction-Controlled Chiral Phosphoric Acid Catalyzed Enantioselective Michael Addition of Difluoroenoxysilanes to Azadienes: a Combination of Experimental and Theoretical Studies. ACS Catal.2022, 12, 9655-9663. (共同一作)

(8). Zhang, Z.#; Chen, H.#; Keller, N.#; Xiong, Q.; Liu, L.; Lan, Y.; Bein, T.; Li, J. Dehydrogenative 6π heterocyclization under visible light irradiation and mechanistic insights. Org. Chem. Front.2021, 8, 3788-3795. (共同一作)

(9). Xu, L.#; Chen, H.#; Liu, J.#; Zhou, L.; Liu, Q.; Lan, Y.; Xiao, J. Chiral Phosphoric Acid Catalyzed Asymmetric C(sp3)–H Functionalization of Biomass-Derived 2,5-Dimethylfuran via Two Sequential Cope-Type Rearrangements. Org. Chem. Front. 2019, 6, 1162-1167. (共同一作)

(10). Zheng, B.#; Chen, H.#; Zhu, L.; Hou, X.; Wang, Y.; Lan, Y.; Peng, Y. Formal Asymmetric Cycloaddition of Activated α,β-Unsaturated Ketones with α-Diazomethylphosphonate Mediated by a Chiral Silver SPINOL Phosphate Catalyst. Org. Lett.2019, 21, 593-597. (共同一作)